Rationale

Nearly one in four U.S. households have someone who suffers from migraine headaches, totaling more than 30 million people.

Intracellular calcium dysregulation has been cited as an important mechanism as a source of migraine headaches. Experts have identified abnormally functioning calcium channels, which transport electrical calcium into the brain cell, as a reason for excessively high levels of calcium and subsequent overstimulation as a key contributor to migraine headaches.